Richard F. Loeser, MD

University of North Carolina

Dr. Richard F. Loeser is the Joseph P. Archie, Jr. Eminent Professor in the Division of Rheumatology, Allergy and Immunology and the Director of the Thurston Arthritis Research Center at the University of North Carolina-Chapel Hill. Dr. Loeser’s lab uses a combination of in vitro experiments with human joint tissue cells and in vivo experiments in rodent models to study cell signaling pathways that regulate anabolic and catabolic activity responsible for joint tissue remodeling and destruction. The lab is particularly interested in determining how reactive oxygen species regulate chondrocyte signaling and how oxidative stress that occurs with aging and joint injury can alter the activity of these signaling pathways and contribute to cell senescence. Dr. Loeser has published over 200 research articles, reviews, chapters and editorials and serves as co-editor of the journal Arthritis and Rheumatology. He received the 2014 OARSI Award for Basic Research in Osteoarthritis.